Connect
Advisor
Dominic D’Agostino, PhD
Biography
Dr. Dominic D’Agostino is a tenured Associate Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine. He runs the website Keto Nutrition, and has been on over 200 podcasts talking about metabolic health.
He is also a Research Scientist at the Institute for Human and Machine Cognition (IHMC). His laboratory develops and tests metabolic-based strategies for targeting CNS oxygen toxicity (seizures), epilepsy, neurodegenerative diseases, brain cancer and metastatic cancer.
The main focus of his lab over the last 12 years has investigating the anticonvulsant and neuroprotective mechanism of the ketogenic diet and ketone metabolite supplementation. This approach can be used to treat a wide variety of pathologies linked pathophysiologically to metabolic dysregulation. Other areas of interest include researching metabolic-based drugs for cancer.
He was a research investigator and crew member on NASA’s Extreme Environment Mission Operation (NEEMO 22) and has a personal interest in environmental medicine and methods to enhance safety and physiological resilience in extreme environments. His research is supported by the Office of Naval Research (ONR), Department of Defense (DoD), private organizations and foundations.
publications
- Heme oxygenase is necessary for the excitatory response of cultured neonatal rat rostral ventrolateral medulla neurons to hypoxia
- Exogenous Ketone Supplements Improved Motor Performance in Preclinical Rodent Models
- Evaluation of the safety and tolerability of a nutritional Formulation in patients with ANgelman Syndrome (FANS): study protocol for a randomized controlled trial
- Effects of an Exogenous Ketone Supplement on Five-Kilometer Running Performance
- The Origin (and Future) of the Ketogenic Diet - by Dr. Dominic D'Agostino and Travis Christofferson